Solomon Kame vs. Nyarlathotep

This is a campaign idea I've had kicking around for a couple of month that I'd like to run, but would much rather play in!

The Ingredients:
The Lamentations of the Flame Princess Weird Fantasy RPG
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One of those epic Chaosium world-sprawling Call of Cthulhu adventures such as Masks of Nyarlathotep
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And run it like a D&D game, with the time period being sometime in the 16th, 17th or 18th century.

Now I gotta see if I can find a copy of the 2e "A Mighty Fortress" sourcebook ...