I'm sure someone has already posted this idea but...
- Presume that you are setting up a multiple DM D&D campaign.
- The DMs get together and use Microscope to determine the history of the milieu; Microscope has mechanics whereas a group could easily ensure that the desired D&D tropes are included.
- The DMs split up the resultant setting into "administrative areas" and each DM runs sessions in their area.
- If the DMs desire, they can use Microscope to further determine details of the setting as the campaign continues.